Carbutamide
Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity[1].
Product Specifications
CAS Number
339-43-5
Product Name Alternative
BZ-55
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/carbutamide.html
Concentration
10mM
Purity
99.43
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(N)C=C1)(NC(NCCCC)=O)=O
Molecular Formula
C11H17N3O3S
Molecular Weight
271.34
Precautions
H315, H319, H335
References & Citations
[1]Kleinsorge H, et al. Carbutamide--the first oral antidiabetic. A retrospect. Exp Clin Endocrinol Diabetes. 1998;106 (2) :149-51.|[2]ROOT MA, et al. Pharmacology of carbutamide (p-aminophenylsulfonyl butylcarbamide) . J Pharmacol Exp Ther. 1957 Apr;119 (4) :468-78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
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