Chlorisondamine
Chlorisondamine is a nicotinic antagonist that acts as a ganglionic blocker and has been utilized to evaluate the neurogenic contributions to blood pressure and sympathetic vasomotor tone in animal models. Chlorisondamine has demonstrated antihypertensive properties, primarily being assessed through its effects on blood pressure, cardiac output, and heart rate in various experimental settings, particularly in mice.
Product Specifications
CAS Number
69-27-2
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chlorisondamine.html
Smiles
ClC1=C(Cl)C(C[N+](C2)(CC[N+](C)(C)C)C)=C2C(Cl)=C1Cl.[Cl-].[Cl-]
Molecular Formula
C14H20Cl6N2
Molecular Weight
429.04
References & Citations
[1]Use of chlorisondamine to assess the neurogenic contribution to blood pressure in mice: An evaluation of method
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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