SG-209
SG-209 is a Nicorandil derivative that produces relaxation through potassium channel activation, while this action contributes to the vasodilating action of Nicorandil (HY-B0341) at higher concentrations. SG-209 dilates tracheal smooth muscle and increases tracheal blood flow in anesthetized dogs[1][2].
Product Specifications
CAS Number
83440-03-3
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sg-209.html
Smiles
O=C(C1=CC=CN=C1)NCCOC(C)=O
Molecular Formula
C10H12N2O3
Molecular Weight
208.21
References & Citations
[1]Ishibashi T, et al. 2-Nicotinamidoethyl acetate (SG-209) is a potassium channel opener: structure activity relationship among nicorandil derivatives. Naunyn Schmiedebergs Arch Pharmacol. 1991 Aug;344 (2) :235-9. |[2]Yonekura H, et al. Effects of N- (2-hydroxyethyl) nicotinamide nitrate (nicorandil; SG-75) and its derivatives on pancreatic exocrine secretion in the dog. Pancreas. 1990;5 (1) :75-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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