20 (S) -Hydroxycholesterol (Standard)
20 (S) -Hydroxycholesterol (Standard) is the analytical standard of 20 (S) -Hydroxycholesterol. This product is intended for research and analytical applications. 20 (S) -hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells[1][2].
Product Specifications
CAS Number
516-72-3
Product Name Alternative
20α-Hydroxycholesterol (Standard)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Reference Standards; Smo
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/20-s-hydroxycholesterol-standard.html
Purity
98.69
Smiles
C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
Molecular Formula
C27H46O2
Molecular Weight
402.65
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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