Trimazosin (hydrochloride hydrate)
Product Specifications
UNSPSC Description
Trimazosin hydrochloride hydrate is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenergic receptor[1][2].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trimazosin-hydrochloride-hydrate.html
Smiles
O=C(OCC(O)(C)C)N1CCN(CC1)C2=NC(N)=C3C=C(C(OC)=C(C3=N2)OC)OC.Cl.O
Molecular Weight
489.95
References & Citations
[1]J Vincent, et al. The cardiovascular effects of trimazosin and prazosin in the rabbit. Clin Exp Pharmacol Physiol. 1986 Aug;13(8):593-608. |[2]H L Elliott, et al. Trimazosin in normotensive subjects. Clin Pharmacol Ther. 1984 Feb;35(2):156-60.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106554A/Trimazosin-hydrochloride-hydrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106554A/
Clinical Information
No Development Reported
CAS Number
53746-46-6
Curated Selection
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