Trimazosin (hydrochloride hydrate)

Trimazosin hydrochloride hydrate is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenergic receptor[1][2].

Product Specifications

CAS Number

[53746-46-6]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/trimazosin-hydrochloride-hydrate.html

Smiles

O=C(OCC(O)(C)C)N1CCN(CC1)C2=NC(N)=C3C=C(C(OC)=C(C3=N2)OC)OC.Cl.O

Molecular Formula

C20H32ClN5O7

Molecular Weight

489.95

References & Citations

[1]J Vincent, et al. The cardiovascular effects of trimazosin and prazosin in the rabbit. Clin Exp Pharmacol Physiol. 1986 Aug;13 (8) :593-608. |[2]H L Elliott, et al. Trimazosin in normotensive subjects. Clin Pharmacol Ther. 1984 Feb;35 (2) :156-60.