Adrenomedullin 2 / Intermedin (Human)

<strong>Adrenomedullin 2 / Intermedin (Human)</strong> <strong>Catalog number:</strong> MDP0783 <strong>CAS Number: </strong>154525-25-4 <strong>Sequence: </strong>Thr-Gln-Ala-Gln-Leu-Leu-Arg-Val-Gly-Cys-Val-Leu-Gly-Thr-Cys-Gln-Val-Gln-Asn-Leu-Ser-His-Arg-Leu-Trp-Gln-Leu-Met-Gly-Pro-Ala-Gly-Arg-Gln-Asp-Ser-Ala-Pro-Val-Asp-Pro-Ser-Ser-Pro-His-Ser-Tyr-NH2 (Disulfide bond between Cys10 and Cys15) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 5100.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Holmes D, Corr M, Thomas G, Harbinson M, Campbell M, Spiers P, Bell D. Protective effects of intermedin/adrenomedullin-2 in a cellular model of human pulmonary arterial hypertension Peptides. 2020 Apr;126:170267. 2: Chauhan M, Balakrishnan M, Yallampalli U, Endsley J, Hankins GD, Theiler R, Yallampalli C. Adrenomedullin 2/intermedin regulates HLA-G in human trophoblasts Biol Reprod. 2011 Dec;85(6):1232-9. 3: Bell D, Gordon BJ, Lavery A, Megaw K, Kinney MO, Harbinson MT. Plasma levels of intermedin (adrenomedullin-2) in healthy human volunteers and patients with heart failure Peptides. 2016 Feb;76:19-29. 4: Hong Y, Hay DL, Quirion R, Poyner DR. The pharmacology of adrenomedullin 2/intermedin Br J Pharmacol. 2012 May;166(1):110-20. 5: Kong L, Xiong Y, Wang D, Huang L, Li M, Feng Z, Zhou Y, Zhang H, Liu F, Xiao F, Wei Y, Zhang W. Intermedin (adrenomedullin 2) promotes breast cancer metastasis via Src/c-Myc-mediated ribosome production and protein translation Breast Cancer Res Treat. 2022 Sep;195(2):91-103. 6: Zhang SY, Xu MJ, Wang X. Adrenomedullin 2/intermedin: a putative drug candidate for treatment of cardiometabolic diseases Br J Pharmacol. 2018 Apr;175(8):1230-1240. 7: Takahashi K, Morimoto R, Hirose T, Satoh F, Totsune K. Adrenomedullin 2/intermedin in the hypothalamo-pituitary-adrenal axis J Mol Neurosci. 2011 Feb;43(2):182-92. 8: Chauhan M, Betancourt A, Balakrishnan M, Mishra A, Espinosa J, Shamshirsaz AA, Fox K, Belfort M, Yallampalli C. Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy Endocrinology. 2022 Jan 1;163(1):bqab204. 9: Pfeil U, Bharathala S, Murtaza G, Mermer P, Papadakis T, Boening A, Kummer W. Spatial expression of components of a calcitonin receptor-like receptor (CRL) signalling system (CRL, calcitonin gene-related peptide, adrenomedullin, adrenomedullin-2/intermedin) in mouse and human heart valves Cell Tissue Res. 2016 Dec;366(3):587-599. <a href="https://pubmed.ncbi.nlm.nih.gov/26743504">10: Bell D, Campbell M, McAleer SF, Ferguson M, Donaghy L, Harbinson MT. Endothelium-derived intermedin/adrenomedullin-2 protects human ventricular cardiomyocytes from ischaemia-reoxygenation injury predominantly via the AM₁ receptor Peptides. 2016 Feb;76:1-13. </a> <br><strong>Products Related to Adrenomedullin 2 / Intermedin (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>