Zilovertamab

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling[1].

Product Specifications

CAS Number

[2485779-13-1]

Product Name Alternative

UC-961; Cirmtuzumab

UNSPSC

12352203

Target

ROR; Wnt

Type

Inhibitory Antibodies

Related Pathways

Metabolic Enzyme/Protease; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zilovertamab.html

Purity

98.21

Solubility

10 mM in DMSO

Smiles

[Zilovertamab]

Molecular Weight

(145.12 kDa)

References & Citations

[1]Liu D, et, al. The Anti-ROR1 Monoclonal Antibody Zilovertamab Inhibits the Proliferation of Ovarian and Endometrial Cancer Cells. Pharmaceutics. 2022 Apr 11;14 (4) :837.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Isoform

Wnt5

Available Sizes

Curated Selection

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