Zilovertamab
Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling[1].
Product Specifications
CAS Number
[2485779-13-1]
Product Name Alternative
UC-961; Cirmtuzumab
UNSPSC
12352203
Target
ROR; Wnt
Type
Inhibitory Antibodies
Related Pathways
Metabolic Enzyme/Protease; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zilovertamab.html
Purity
98.21
Solubility
10 mM in DMSO
Smiles
[Zilovertamab]
Molecular Weight
(145.12 kDa)
References & Citations
[1]Liu D, et, al. The Anti-ROR1 Monoclonal Antibody Zilovertamab Inhibits the Proliferation of Ovarian and Endometrial Cancer Cells. Pharmaceutics. 2022 Apr 11;14 (4) :837.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Isoform
Wnt5
Available Sizes
Curated Selection
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