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Sulfamerazine

Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes[1].

Product Specifications

CAS Number

127-79-7

Product Name Alternative

RP2632

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sulfamerazine.html

Concentration

10mM

Purity

99.82

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

O=S(C1=CC=C(N)C=C1)(NC2=NC=CC(C)=N2)=O

Molecular Formula

C11H12N4O2S

Molecular Weight

264.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Aday B, et al. Synthesis of novel sulfonamide analogs containing sulfamerazine/sulfaguanidine and their biological activities. J Enzyme Inhib Med Chem. 2016 Dec;31 (6) :1005-10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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