NPC 17731
NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively[1].
Product Specifications
CAS Number
147267-10-5
UNSPSC
12352209
Target
Bradykinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/npc-17731.html
Smiles
O=C([C@@H]1N(C[C@H](C1)OCCC)C([C@H](CO)NC([C@@H](NC(CNC([C@H]2N(C[C@@H](C2)O)C([C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC([C@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)N5[C@]6([H])[C@](CCCC6)([H])C[C@H]5C(N[C@H](C(O)=O)CCCNC(N)=N)=O
Molecular Formula
C59H95N19O14
Molecular Weight
1294.50
References & Citations
[1]Y S Medeiros, et al. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. Gen Pharmacol. 1995 Nov;26 (7) :1507-11.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OM618410 96 Strip Well
Bovine high affinity immunoglobulin epsilon receptor subunit alpha autoantibody (FCER1A Ab) ELISA Kit
Sign In for Pricing
View Details 
130175-ML490 100 µL
NCBP2 (Nuclear Cap-binding Protein Subunit 2, 20kD Nuclear Cap-binding Protein, NCBP 20kD Subunit, CBP20, NCBP-interacting Protein 1, NIP1, Cell Proliferation-inducing Gene 55 Protein, CBP20, PIG55) (MaxLight 490)
Sign In for Pricing
View Details