BMS-986308
Product Specifications
UNSPSC Description
BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research[1].
Target Antigen
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bms-986308.html
Smiles
CC1=C(COC2=O)C2=CC=C1[C@@H]3CN(C[C@@H](N3)C)CC4=NN(C5=CC(C)=C(C=N5)C#N)N=C4
Molecular Weight
443.50
References & Citations
[1]Jeremy M Richter, et al. Discovery of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor for the Treatment of Heart Failure. J Med Chem. 2024 Jun 13;67(11):9731-9744.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162555/BMS-986308-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162555/
Clinical Information
Phase 1
CAS Number
2254333-97-4
Curated Selection
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