Brain Natriuretic Peptide Agonist of Guanylyl cyclase-A

<strong>Brain Natriuretic Peptide Agonist of Guanylyl cyclase-A</strong>_x000D_ <strong>Catalog number:</strong> B2019205_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> BNP;BNP(1-32);BNP-32;brain natriuretic peptide 32;Natrecor_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Holditch SJ, Schreiber CA, Harris PC, LaRusso NF, Ramirez-Alvarado M, Cataliotti A, Torres VE, Ikeda Y. B-type natriuretic peptide overexpression ameliorates hepatorenal fibrocystic disease in¬†a¬†rat¬†model of polycystic kidney disease Kidney Int. 2017 Sep;92(3):657-668._x000D_ 2: Yu YC, Cao LH, Yang XL. Modulation by brain natriuretic peptide of GABA receptors on rat retinal ON-type bipolar cells J Neurosci. 2006 Jan 11;26(2):696-707._x000D_ 3: Parat M, McNicoll N, Wilkes B, Fournier A, De L√©an A. Role of extracellular domain dimerization in agonist-induced activation of natriuretic peptide receptor A Mol Pharmacol. 2008 Feb;73(2):431-40._x000D_ 4: Schoenfeld JR, Sehl P, Quan C, Burnier JP, Lowe DG. Agonist selectivity for three species of natriuretic peptide receptor-A Mol Pharmacol. 1995 Jan;47(1):172-80._x000D_ 5: Chen Y, Harty GJ, Huntley BK, Iyer SR, Heublein DM, Harders GE, Meems L, Pan S, Sangaralingham SJ, Ichiki T, Burnett JC Jr. CRRL269: a novel designer and renal-enhancing pGC-A peptide activator Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R407-R414._x000D_ 6: Labrecque J, Mc Nicoll N, Marquis M, De L√©an A. A disulfide-bridged mutant of natriuretic peptide receptor-A displays constitutive activity. Role of receptor dimerization in signal transduction J Biol Chem. 1999 Apr 2;274(14):9752-9._x000D_ 7: Marchenkova A, van den Maagdenberg AM, Nistri A. Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1 Neuroscience. 2016 Sep 7;331:197-205._x000D_ 8: Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart Circ Res. 2010 Jun 25;106(12):1849-60._x000D_ 9: Edelson JD, Makhlina M, Silvester KR, Vengurlekar SS, Chen X, Zhang J, Koziol-White CJ, Cooper PR, Hallam TJ, Hay DW, Panettieri RA Jr. In¬†vitro and in¬†vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH(2)) natriuretic peptide receptor-A agonist that is resistant to neutral¬†endopeptidase and acts as a bronchodilator Pulm Pharmacol Ther. 2013 Apr;26(2):229-38._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26517044">10: Tokudome T, Kishimoto I, Shindo T, Kawakami H, Koyama T, Otani K, Nishimura H, Miyazato M, Kohno M, Nakao K, Kangawa K. Importance of Endogenous Atrial and Brain Natriuretic Peptides in Murine Embryonic Vascular and Organ Development Endocrinology. 2016 Jan;157(1):358-67. </a>_x000D_ _x000D_ <strong>Products Related to Brain Natriuretic Peptide Agonist of Guanylyl cyclase-A can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>