BET BD2-IN-3
BET BD2-IN-3 (compound I-58) is an inhibitor of BET, targeting the BD2 domain of BET. BET BD2-IN-3 can be radiolabeled with [11C] for positron emission tomography (PET) imaging. BET [11C]BD2-IN-3 showed suitable biodistribution in peripheral organs and tissues in PET applications in mice[1].
Product Specifications
CAS Number
2677039-66-4
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bet-bd2-in-3.html
Smiles
O=C1N(C)C2=CC3=CC=CC=C3N(CC4=CC=CC(NC5CCN(C)CC5)=C4)C6=CC=CC1=C26
Molecular Formula
C29H30N4O
Molecular Weight
450.57
References & Citations
[1]Development and Evaluation of [11C]I-58: A Novel PET Radiotracer Targeting BRD4 BD2 for Advanced Epigenetic Imaging
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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