InsB (9-23)

InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes[1].

Product Specifications

CAS Number

[163364-16-7]

Product Name Alternative

Insulin B chain (9-23)

UNSPSC

12352209

Target

MHC

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/insb-9-23.html

Purity

98.98

Solubility

H2O

Smiles

O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CS)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N

Molecular Formula

C72H116N20O22S1

Molecular Weight

1645.90

References & Citations

[1]Georgia Fousteri, et al. InsB:9-23 peptide-based immunotherapy for type 1 diabetes; the immunization frequency and the state of the disease can alter the efficacy. Immunology. 2008 Apr.