Sp-cGMPS

Sp-cGMPS is an activator of cGMP-dependent protein kinases (PKGs) . Sp-cGMPS can be used in cardiovascular disease-related research[1].

Product Specifications

CAS Number

[86562-10-9]

UNSPSC

12352005

Target

PKG

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sp-cgmps.html

Smiles

O=C1C2=C(NC(N)=N1)N([C@@](O[C@@](CO3)([H])[C@@]4([H])O[P@]3(S)=O)([H])[C@@H]4O)C=N2

Molecular Formula

C10H12N5O6PS

Molecular Weight

361.27

References & Citations

[1]Archer SL, et al. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 2;91 (16) :7583-7. |[2]Butt E, et al. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp) -8-bromo-PET-cyclic GMPS. Br J Pharmacol. 1995 Dec;116 (8) :3110-6.