Sp-cGMPS
Sp-cGMPS is an activator of cGMP-dependent protein kinases (PKGs) . Sp-cGMPS can be used in cardiovascular disease-related research[1].
Product Specifications
CAS Number
86562-10-9
UNSPSC
12352005
Target
PKG
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sp-cgmps.html
Smiles
O=C1C2=C(NC(N)=N1)N([C@@](O[C@@](CO3)([H])[C@@]4([H])O[P@]3(S)=O)([H])[C@@H]4O)C=N2
Molecular Formula
C10H12N5O6PS
Molecular Weight
361.27
References & Citations
[1]Archer SL, et al. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 2;91 (16) :7583-7. |[2]Butt E, et al. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp) -8-bromo-PET-cyclic GMPS. Br J Pharmacol. 1995 Dec;116 (8) :3110-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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