Nafadotride
Nafadotride is a dopamine D3 receptor antagonist. Nafadotrode regulates dopamine signaling primarily by antagonizing dopamine D3 receptors. The dopamine D3 receptor plays an important role in regulating emotion, motivation, reward, and certain motor functions. By blocking these receptors, Nafadotrode may affect neurotransmission processes associated with these functions. Nafadotrode can be used to explore the role of dopamine D3 receptors in various behavioral and neuropsychiatric disorders[1].
Product Specifications
CAS Number
[149649-22-9]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nafadotride.html
Purity
99.78
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C(C(NCC2N(CCC2)CCCC)=O)C=C(C#N)C3=CC=CC=C13
Molecular Formula
C22H27N3O2
Molecular Weight
365.47
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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