Angeloylbinankadsurin A
Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM) . Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM) [1].
Product Specifications
CAS Number
[77165-80-1]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/angeloylbinankadsurin-a.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C)=C/C)O[C@H]1C2=C(C3=C(C(OC)=C(C=C3C[C@H]([C@H]1C)C)OC)O)C(OC)=C4OCOC4=C2
Molecular Formula
C27H32O8
Molecular Weight
484.54
References & Citations
[1]Yang Y, et al. New Lignans from roots of Kadsura coccinea. Fitoterapia. 2019 Nov;139:104368.|[2]Yang Y. et al. New Lignans from roots of Kadsura coccinea. Fitoterapia. 2019 Nov;139:104368.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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