Angeloylbinankadsurin A

Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM) . Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM) [1].

Product Specifications

CAS Number

[77165-80-1]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/angeloylbinankadsurin-a.html

Solubility

10 mM in DMSO

Smiles

O=C(/C(C)=C/C)O[C@H]1C2=C(C3=C(C(OC)=C(C=C3C[C@H]([C@H]1C)C)OC)O)C(OC)=C4OCOC4=C2

Molecular Formula

C27H32O8

Molecular Weight

484.54

References & Citations

[1]Yang Y, et al. New Lignans from roots of Kadsura coccinea. Fitoterapia. 2019 Nov;139:104368.|[2]Yang Y. et al. New Lignans from roots of Kadsura coccinea. Fitoterapia. 2019 Nov;139:104368.