(+) -JJ-74-138
(+) -JJ-74-138, a novel non-competitive androgen receptor (AR) antagonist, is capable of inhibiting Enzalutamide-resistant CRPC[1].
Product Specifications
CAS Number
[2135545-34-3]
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-jj-74-138.html
Smiles
O=C(N1CCN(C2=CC(C(F)(F)F)=CC=C2C)CC1)[C@H]3[C@@H](C4=CC(S(F)(F)(F)(F)F)=CC=C4)C3
Molecular Formula
C22H22F8N2OS
Molecular Weight
514.48
References & Citations
[1] (+) -JJ-74-138 is a Novel Noncompetitive Androgen Receptor Antagonist. Mol Cancer Ther. 2022 Apr 1;21 (4) :483-492.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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