(+) -JJ-74-138

(+) -JJ-74-138, a novel non-competitive androgen receptor (AR) antagonist, is capable of inhibiting Enzalutamide-resistant CRPC[1].

Product Specifications

CAS Number

[2135545-34-3]

UNSPSC

12352005

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plus-jj-74-138.html

Smiles

O=C(N1CCN(C2=CC(C(F)(F)F)=CC=C2C)CC1)[C@H]3[C@@H](C4=CC(S(F)(F)(F)(F)F)=CC=C4)C3

Molecular Formula

C22H22F8N2OS

Molecular Weight

514.48

References & Citations

[1] (+) -JJ-74-138 is a Novel Noncompetitive Androgen Receptor Antagonist. Mol Cancer Ther. 2022 Apr 1;21 (4) :483-492.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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