MBX3135
MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics[1].
Product Specifications
CAS Number
1636878-36-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mbx3135.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1=CC=C(C=C1)CCSC2=NC(N3CC(OC(C3)C)C)=C4COC(C)(CC4=C2C#N)C)=O
Molecular Formula
C28H34N4O3S
Molecular Weight
506.66
References & Citations
[1]Sjuts H, et al. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc Natl Acad Sci U S A. 2016 Mar 29;113 (13) :3509-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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