MCP-2/CCL8, Human (SUMO)
MCP-2/CCL8 Protein, Human (SUMO) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Human (SUMO) is a recombinant human MCP-2/CCL8 (Q24-P99) protein expressed by E. coli with a N-SUMO tag[1][2].
Product Specifications
Product Name Alternative
MCP-2/CCL8 Protein, Human (SUMO), Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/mcp-2-ccl8-protein-human-sumo.html
Molecular Formula
6355 (Gene_ID) P80075 (Q24-P99) (Accession)
Molecular Weight
Approximately 30 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
[1]Xiang Zhang, et al. CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling. Lab Invest. 2020 Apr;100 (4) :619-629.|[2]Jan Korbecki, et al. CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4. Int J Mol Sci. 2020 Nov 9;21 (21) :8412.|[3]Jian Zhou, et al. MCP2 activates NF-κB signaling pathway promoting the migration and invasion of ESCC cells. Cell Biol Int. 2018 Mar;42 (3) :365-372.
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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