Prolylisoleucine
Prolylisoleucine (Pro-Ile) is a dipeptide composed of Proline and Isoleucine, as well as a blocker of endopeptidase 24.16[1].
Product Specifications
CAS Number
51926-51-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/prolylisoleucine.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1NCCC1)=O
Molecular Formula
C11H20N2O3
Molecular Weight
228.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]H Shiraishi, et al. Taste of Proline-containine Peptides, Agricultural and Biological Chemistry, Volume 37, Issue 10, 1 October 1973, Pages 2427–2428|[2]Barelli H, et al. Potent inhibition of endopeptidase 24.16 and endopeptidase 24.15 by the phosphonamide peptide N- (phenylethylphosphonyl) -Gly-L-Pro-L-aminohexanoic acid. Biochem J. 1992 Oct 15;287 (Pt 2) (Pt 2) :621-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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