HCAII-IN-8
HCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].
Product Specifications
CAS Number
[952306-80-8]
UNSPSC
12352005
Hazard Statement
H319
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaii-in-8.html
Purity
99.41
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C=C1OC)C(NC2=CC(S(N)(=O)=O)=CC=C2)=O
Molecular Formula
C15H16N2O5S
Molecular Weight
336.36
Precautions
P264-P280-P305+P351+P338
References & Citations
[1]Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7 (50) :47251-47264.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II
Available Sizes
Curated Selection
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