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Pan-KRAS ligand 1

Pan-KRAS ligand 1 is a Ligand for Target Protein for PROTAC. pan-KRAS ligand 1 can be used for synthesis PROTAC pan-KRAS degrader 4.

Product Specifications

CAS Number

2886012-31-1

UNSPSC

12352101

Target

Ligands for Target Protein for PROTAC; Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pan-kras-ligand-1.html

Smiles

O=CCOC1=NC2=C(C(C3=C4C(C#C)=C(F)C=CC4=CC(O)=C3)=NC=C2C(N5CC6N(C(CC6)C5)C(OC(C)(C)C)=O)=N1)F

Molecular Formula

C32H29F2N5O5

Molecular Weight

601.60

References & Citations

[1]Jesus Raul Medina. Cereblon-based kras degrading protacs and uses related thereto. US20240287101A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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