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Anti-Mouse CCR3/CD193 Antibody (6S2-19-4)

Anti-Mouse CCR3/CD193 Antibody (6S2-19-4) is a rat-derived IgG2b λ type antibody inhibitor, targeting to mouse CCR3/CD193. Anti-Mouse CCR3/CD193 Antibody (6S2-19-4) can deplete eosinophils. Anti-Mouse CCR3/CD193 Antibody (6S2-19-4) can be used for the researches of cancer, infection, inflammation and immunology, such as lymphoma, ileitis and strongyloides stercoralis infection[1][2][3][4].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

CCR

Type

Inhibitory Antibodies

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-ccr3-cd193-antibody-6s2-19-4.html

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCCR3/CD193Antibody(6S2-19-4)]

Molecular Weight

(150 kDa)

References & Citations

[1]Galioto AM, et al. Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval strongyloides stercoralis in mice. Infect Immun. 2006 Oct;74 (10) :5730-8. |[2]Masterson JC, et al. CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling. Am J Pathol. 2011 Nov;179 (5) :2302-14.|[3]Jia Q, et al. Peripheral eosinophil counts predict efficacy of anti-CD19 CAR-T cell therapy against B-lineage non-Hodgkin lymphoma. Theranostics. 2021 Mar 4;11 (10) :4699-4709.|[4]Yang M, et al. Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. J Allergy Clin Immunol. 2003 Nov;112 (5) :935-43.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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