Sifalimumab Antibody
Sifalimumab (MEDI-545) is a human monoclonal antibody that neutralizes interferon-alpha (IFNα) to modulate aberrant immune responses. It has been investigated in clinical and preclinical research for systemic lupus erythematosus (SLE), with studies exploring its effects on disease biomarkers in both in vitro assays and in vivo models.
Product Specifications
Product Name Alternative
MEDI-545, MDX-1103, IFN-α
Target
IFNAR, COX
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation, Neuroscience
Concentration
5.78 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
144.24 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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