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Sifalimumab Antibody

Sifalimumab (MEDI-545) is a human monoclonal antibody that neutralizes interferon-alpha (IFNα) to modulate aberrant immune responses. It has been investigated in clinical and preclinical research for systemic lupus erythematosus (SLE), with studies exploring its effects on disease biomarkers in both in vitro assays and in vivo models.

Product Specifications

Product Name Alternative

MEDI-545, MDX-1103, IFN-α

Target

IFNAR, COX

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation, Neuroscience

Concentration

5.78 mg/mL

Purity

95.00% (May vary between batches)

Molecular Weight

144.24 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

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