Itolizumab Antibody
Itolizumab is a humanized recombinant monoclonal antibody targeting the CD6 receptor, specifically its SRCR domain 1. It functions by modulating T-cell activation, suppressing proliferation and pro-inflammatory cytokine release. This mechanism supports its research applications in studying autoimmune diseases like psoriasis and rheumatoid arthritis, as well as inflammatory conditions including COVID-19, in both in vitro and in vivo experimental models.
Product Specifications
Product Name Alternative
Itolizumab, EQ 001, EQ001, EQ-001
Target
Others, Immunology/Inflammation related
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
12.76 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
144.82 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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