Demcizumab Antibody
Demcizumab (OMP-21M18) is a humanized monoclonal antibody targeting DLL4, functioning as a potent Notch signaling pathway inhibitor. It has demonstrated efficacy in preclinical cancer models, including in vivo tumor xenograft studies, both as a monotherapy and in combination with standard chemotherapeutics.
Product Specifications
Product Name Alternative
Demcizumab, OMP 21M18, Notch, Gammasecretase
Target
Gamma-secretase
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Concentration
5.82 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
145.34 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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