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Demcizumab Antibody

Demcizumab (OMP-21M18) is a humanized monoclonal antibody targeting DLL4, functioning as a potent Notch signaling pathway inhibitor. It has demonstrated efficacy in preclinical cancer models, including in vivo tumor xenograft studies, both as a monotherapy and in combination with standard chemotherapeutics.

Product Specifications

Product Name Alternative

Demcizumab, OMP 21M18, Notch, Gammasecretase

Target

Gamma-secretase

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Concentration

5.82 mg/mL

Purity

>95% (May vary between batches)

Molecular Weight

145.34 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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