Seribantumab Antibody
Seribantumab (MM-121) is a humanized anti-HER3 monoclonal antibody that blocks NRG1-mediated signaling, suppressing growth in breast and lung cancer models with NRG1 alterations and inducing apoptosis in specific cell lines. It has been investigated in both in vitro and in vivo studies for targeting HER3-dependent cancers.
Product Specifications
Product Name Alternative
MM121, MM-121, SAR256212, SAR-256212
Target
Apoptosis, HER, EGFR
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Concentration
9.41 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
143.14 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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