Patritumab Antibody
Patritumab (U3-1287) is a human monoclonal antibody targeting HER3, which exerts antitumor effects by inhibiting the phosphorylation of HER3, EGFR, HER2, ERK, and AKT pathways. It has demonstrated the ability to induce apoptosis and suppress proliferation in non-small cell lung cancer models in both in vitro and in vivo studies.
Product Specifications
Product Name Alternative
U3-1287, ERK, EGFR, HER, AMG-888, Akt
Target
EGFR, Akt, HER, PARP, Survivin, ERK
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Concentration
2.71 mg/mL
Purity
95.20% (May vary between batches)
Molecular Weight
146.97 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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