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Patritumab Antibody

Patritumab (U3-1287) is a human monoclonal antibody targeting HER3, which exerts antitumor effects by inhibiting the phosphorylation of HER3, EGFR, HER2, ERK, and AKT pathways. It has demonstrated the ability to induce apoptosis and suppress proliferation in non-small cell lung cancer models in both in vitro and in vivo studies.

Product Specifications

Product Name Alternative

U3-1287, ERK, EGFR, HER, AMG-888, Akt

Target

EGFR, Akt, HER, PARP, Survivin, ERK

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Concentration

2.71 mg/mL

Purity

95.20% (May vary between batches)

Molecular Weight

146.97 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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