Dalotuzumab Antibody
Dalotuzumab (MK-0646) is a humanized anti-IGF-1R monoclonal antibody that blocks oncogenic signaling, promoting tumor cell apoptosis and cell cycle arrest. Its research applications include in vitro studies of IGF-1R pathway inhibition and in vivo combination therapy models for various cancers, demonstrating synergistic effects with chemotherapeutic agents.
Product Specifications
Product Name Alternative
H7C10, MK-0646
Target
IGF-1R, Apoptosis
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Cell Biology, Signal Transduction
Concentration
6.13 mg/mL
Purity
97.60% (May vary between batches)
Molecular Weight
146.36 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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