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Lexatumumab Antibody

Lexatumumab (GHS-ETR2) is a human agonistic monoclonal antibody targeting TRAIL-R2 (DR5) to induce apoptosis in cancer cells. It is a research tool for studying malignant pleural mesothelioma (MPM), with demonstrated pro-apoptotic activity in both in vitro cell cultures and in vivo xenograft models.

Product Specifications

Product Name Alternative

Apoptosis, DR5 mAB, Lexatumumab, HGS-ETR 2, ETR2-ST01, TRAIL

Target

Apoptosis

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Concentration

4.69 mg/mL

Purity

>95% (May vary between batches)

Molecular Weight

143.48 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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