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Tarextumab Antibody

Tarextumab (OMP-59R5) is a fully human IgG2 monoclonal antibody that selectively inhibits Notch2 and Notch3 receptors. Preclinical and clinical evidence supports its efficacy in epithelial cancers like pancreatic, lung, and ovarian cancer, making it a promising candidate for oncology research. Its utility extends to in vitro signaling studies and in vivo tumor model experiments.

Product Specifications

Product Name Alternative

Anti-Human NOTCH2 Recombinant Antibody, OMP 59R5

Target

Gamma-secretase

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Concentration

13.567 mg/mL

Purity

≥95% (May vary between batches)

Molecular Weight

~150 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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