Ascrinvacumab Antibody
Ascrinvacumab (PF-03446962) is a humanized IgG2 monoclonal antibody targeting ALK-1 with high affinity (Kd = 7 nM) . It functions as an inhibitor of TGF-β signaling and is utilized in research applications for hepatocellular carcinoma (HCC), including in vitro and in vivo experimental models.
Product Specifications
Product Name Alternative
Ascrinvacumab, ALK1, TGFbeta/Smad, TGF-beta/Smad, TGF-beta, TGF-β/Smad, TGFβ, TGF-b/Smad, TGFbeta, TGFb, Smad, PF03446962, PF-03446962, PF 03446962
Target
ALK, TGF-beta/Smad
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Concentration
9.31 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
150 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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