Petosemtamab Antibody
Petosemtamab (MCLA-158) is a potent bispecific antibody targeting EGFR and LGR5, disrupting oncogenic signaling and inducing receptor degradation. It is utilized in preclinical research for solid tumors, including head and neck squamous cell carcinoma and colorectal cancer, with studies demonstrating activity in both in vitro and in vivo models.
Product Specifications
Product Name Alternative
Petosemtamab, MCLA 158, MCLA158, MCLA-158, EGFR
Target
EGFR
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Signal Transduction
Concentration
6.98 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
145.97 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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