Astegolimab Antibody
Astegolimab (RG 6149) is a humanized IgG2 monoclonal antibody designed to inhibit IL-33 signaling by targeting its receptor. It is a key research tool for investigating the mechanisms of chronic obstructive pulmonary disease (COPD) and severe asthma, with applications in both in vitro cellular assays and in vivo preclinical models.
Product Specifications
Product Name Alternative
MSTT 1041A, Interleukin Related, RG 6149
Target
NF-κB, Interleukin, MDM-2/p53
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Concentration
2.58 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
144.98 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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