Carotuximab Antibody
Carotuximab (DE-122) is a CD105-targeting antibody that inhibits Smad signaling, exerting potent antiangiogenic and immunomodulatory effects. It is utilized in oncology and vascular biology research to study endothelial dysfunction in models of hypercholesterolemia and hyperglycemia, both in vitro and in vivo.
Product Specifications
Product Name Alternative
Carotuximab, CD105, DE122, DE-122, DE 122, Immunology related, Immunologyrelated, Inflammation related, Inflammationrelated, Smad, TGFb, TGF-b/Smad, TGFβ, TGF-β/Smad, TGF-beta, TGFbeta, TGF-beta/Smad, TGFbeta/Smad, TRC 105, TRC105, TRC-105
Target
TGF-beta/Smad, Immunology/Inflammation related
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation, Stem Cell & Developmental Biology
Concentration
9.07 mg/mL
Purity
>95% (May vary between batches)
Molecular Weight
144.8 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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