Tozorakimab Antibody
Tozorakimab (MEDI-3506) is a human IgG1 monoclonal antibody that neutralizes IL-33, blocking its signaling via the ST2 and RAGE/EGFR receptors. This inhibition reduces inflammatory responses and epithelial dysfunction, making it a valuable research tool for investigating COPD pathogenesis in both in vitro and in vivo experimental models.
Product Specifications
Product Name Alternative
MEDI 3506, MEDI3506, MEDI-3506
Target
Interleukin, Others
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
5.01 mg/mL
Purity
96.03% (May vary between batches)
Molecular Weight
144.65 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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