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Ipafricept Antibody

Ipafricept (OMP-54F28) is a Wnt pathway inhibitor composed of a human frizzled-8 receptor decoy fused to an IgG1 Fc fragment. It acts by sequestering Wnt ligands, demonstrating antitumor activity in preclinical studies of solid tumors, including in vivo models of ovarian and pancreatic cancers.

Product Specifications

Product Name Alternative

OMP54F28, OMP-54F28, FZD8Fc, FZD8-Fc, bcatenin, betacatenin, beta-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin

Target

Wnt/beta-catenin

Clonality

Recombinant

Conjugation

Unconjugated

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Concentration

7.95 mg/mL

Purity

97.40% (May vary between batches)

Molecular Weight

41.12 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

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