Ipafricept Antibody
Ipafricept (OMP-54F28) is a Wnt pathway inhibitor composed of a human frizzled-8 receptor decoy fused to an IgG1 Fc fragment. It acts by sequestering Wnt ligands, demonstrating antitumor activity in preclinical studies of solid tumors, including in vivo models of ovarian and pancreatic cancers.
Product Specifications
Product Name Alternative
OMP54F28, OMP-54F28, FZD8Fc, FZD8-Fc, bcatenin, betacatenin, beta-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin
Target
Wnt/beta-catenin
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Concentration
7.95 mg/mL
Purity
97.40% (May vary between batches)
Molecular Weight
41.12 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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