Izalontamab Antibody
Izalontamab (SI-B001) is a bispecific antibody targeting EGFR and HER3, designed to inhibit both EGFR homodimers and EGFR/HER3 heterodimers to block oncogenic signaling. It is used in research for advanced epithelial cancers like NSCLC and HNSCC, with studies demonstrating its activity in both in vitro and in vivo models.
Product Specifications
Product Name Alternative
SIB001, SI-B001
Target
HER, EGFR
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Signal Transduction
Concentration
5.11 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
197.21 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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