Cusatuzumab Antibody
Cusatuzumab (ARGX-110) is an enhanced human monoclonal antibody targeting CD70. It inhibits the CD70/CD27 signaling axis and mediates the elimination of CD70-positive leukemic stem cells (LSCs), as demonstrated in both in vitro studies and in vivo xenograft models. This makes it a relevant tool for oncology research, particularly in studying acute myeloid leukemia (AML) and other CD70-expressing malignancies.
Product Specifications
Product Name Alternative
JNJ4550, JNJ-4550, JNJ74494550, JNJ 74494550, ARGX110, ARGX-110
Target
Immunology/Inflammation related, Apoptosis
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Immunology & Inflammation
Concentration
8.15 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
144.34 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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