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Cusatuzumab Antibody

Cusatuzumab (ARGX-110) is an enhanced human monoclonal antibody targeting CD70. It inhibits the CD70/CD27 signaling axis and mediates the elimination of CD70-positive leukemic stem cells (LSCs), as demonstrated in both in vitro studies and in vivo xenograft models. This makes it a relevant tool for oncology research, particularly in studying acute myeloid leukemia (AML) and other CD70-expressing malignancies.

Product Specifications

Product Name Alternative

JNJ4550, JNJ-4550, JNJ74494550, JNJ 74494550, ARGX110, ARGX-110

Target

Immunology/Inflammation related, Apoptosis

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Cell Biology, Immunology & Inflammation

Concentration

8.15 mg/mL

Purity

95.00% (May vary between batches)

Molecular Weight

144.34 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

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