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Fremanezumab Antibody

Fremanezumab is a humanized anti-CGRP monoclonal antibody for migraine prophylaxis research. It potently neutralizes CGRP across species, inhibiting its vasodilatory effects in vivo and suppressing meningeal nociceptive neuron activation in rat CSD models. In vitro, it also counteracts CGRP-mediated immunosuppression on microglia and lymphocytes.

Product Specifications

Product Name Alternative

LBR-101, PF-04427429, RN-307, TEV48125, TEV-48125

Target

CGRP Receptor

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Concentration

5.28 mg/mL

Purity

95.00% (May vary between batches)

Molecular Weight

145.49 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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