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Tilvestamab Antibody

Tilvestamab (BGB149) is a humanized anti-AXL antibody with dual anti-tumor and anti-fibrotic properties. It functions by blocking Gas6-induced AXL activation, thereby inhibiting tumor progression, as demonstrated in studies using 786-0 renal cell carcinoma cells. This investigational antibody is a valuable tool for oncology and fibrosis research in both in vitro and in vivo models.

Product Specifications

Product Name Alternative

BGB 149, BGB149

Target

TAM Receptor

Conjugation

Unconjugated

Field of Research

Signal Transduction

Concentration

7.29 mg/mL

Purity

>95% (May vary between batches)

Molecular Weight

146.22 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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