Crovalimab Antibody
Crovalimab is an engineered humanized anti-C5 monoclonal antibody that inhibits terminal complement activation by blocking C5 cleavage, thereby preventing MAC formation and intravascular hemolysis. Its pH-dependent FcRn recycling extends its half-life, making it a relevant therapeutic candidate for research in complement-mediated diseases like PNH, supported by in vitro and in vivo studies.
Product Specifications
Product Name Alternative
SKY 59, SKY59, RO7112689, RO 7112689
Target
Complement System
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
25.521 mg/mL
Purity
≥95% (May vary between batches)
Molecular Weight
~150 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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